2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride - Names and Identifiers

Name	KRP-203
Synonyms	KRP203 KRP-203 KRP203 KRP-203 (hydrochloride) 2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol 2-AMINO-2-[2-[2-CHLORO-4-[[3-(PHENYLMETHOXY)PHENYL]THIO]PHENYL]ETHYL]-1,3-PROPANEDIOL HCL 2-AMINO-2-(4-((3-(BENZYLOXY)PHENYL)THIO)-2-CHLOROPHENETHYL)PROPANE-1,3-DIOL HYDROCHLORIDE 2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chloro-phenethyl)propane-1,3-diol hydrochloride 2-Amino-2-(2-(4-(3-benzyloxyphenylthio)-2-chlorophenyl)ethyl)-1,3-propanediol hydrochloride 2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol Hydrochloride 2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride 2-amino-2-[2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl]propane-1,3-diol hydrochloride
CAS	509088-69-1
EINECS	1312995-182-4
InChI	InChI=1/C24H26ClNO3S.ClH/c25-23-14-22(10-9-19(23)11-12-24(26,16-27)17-28)30-21-8-4-7-20(13-21)29-15-18-5-2-1-3-6-18;/h1-10,13-14,27-28H,11-12,15-17,26H2;1H

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride - Physico-chemical Properties

Molecular Formula	C24H27Cl2NO3S
Molar Mass	480.45
Melting Point	199-200 ºC (DEC.)
Boling Point	657.1°C at 760 mmHg
Flash Point	351.2°C
Solubility	DMSO, Methanol
Vapor Presure	3.67E-18mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	Refrigerator

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride - Introduction

KRP-203(KRP-203) is a compound with the chemical name (S)-3-((S)-2-(m-(p-chlorophenyl) pentafluoromethylpyridinyl) propionic acid)-4-(3-methoxyphenyl)-2-hydroxy-2-methylbutanoic acid.

The main use of the KRP-203 is as an immunosuppressant, especially for the prevention and treatment of transplant rejection after organ transplantation. It inhibits the function of the immune system and reduces the activity and lethality of immune cells, thereby reducing the rejection after organ transplantation.

The method for preparing KRP-203 is to first synthesize (S)-3-(2-(p-chlorophenyl) pentafluoromethylphenyl) propionyl chloride, and then react with 2-methoxyphenol to generate the target product.

In terms of safety, KRP-203 is a toxic compound and requires attention to safe operation. Be careful to avoid contact with skin and eyes, and seek medical help immediately if ingested or inhaled. When using KRP-203, follow appropriate precautions, such as wearing protective gloves and eye protection.

Last Update：2024-04-09 19:05:50

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2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride

KRP-203

CAS: 509088-69-1

Molecular Formula: C24H27Cl2NO3S

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride - Names and Identifiers

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride - Physico-chemical Properties

2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol hydrochloride - Introduction

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